The impact of Cytochrome P450 CYP1A2, CYP2C9, CYP2C19 and CYP2D6 genes on suicide attempt and suicide risk-a European multicentre study on treatment-resistant major depressive disorder.

doi:10.1007/s00406-012-0375-y

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The impact of Cytochrome P450 CYP1A2, CYP2C9, CYP2C19 and CYP2D6 genes on suicide attempt and suicide risk-a European multicentre study on treatment-resistant major depressive disorder.

European archives of psychiatry and clinical neuroscience - 1 Aug 2013

Höfer Peter, Schosser Alexandra, Calati Raffaella, Serretti Alessandro, Massat Isabelle, Kocabas Neslihan Aygun, Konstantinidis Anastasios, Linotte Sylvie, Mendlewicz Julien, Souery Daniel, Zohar Joseph, Juven-Wetzler Alzbeta, Montgomery Stuart, Kasper Siegfried

Abstract excerpt

Recently published data have reported associations between cytochrome P450 metabolizer status and suicidality. The aim of our study was to investigate the role of genetic polymorphisms of the cytochrome P450 genes on suicide risk and/or a personal history of suicide attempts. Two hundred forty-three major depressive disorder patients were collected in the context of a European multicentre resistant depression...

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PMID: 23081704
DOI: 10.1007/s00406-012-0375-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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