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Article

Completed suicides of citalopram users-the role of CYP genotypes and adverse drug interactions.

International journal of legal medicine - 1 Mar 2019

Rahikainen Anna-Liina, Vauhkonen P, Pett H, Palo J U, Haukka J, Ojanperä I, Niemi M, Sajantila Antti

Abstract excerpt

Depression is known to be a risk factor for suicide. Currently, the most used antidepressants are selective serotonin reuptake inhibitors (SSRIs). Not all users, however, benefit from them. In such cases, treatment failure can be explained in part by genetic differences. In this study, we investigated the role of pharmacogenetic factors in citalopram-positive completed suicides (n = 349). Since citalopram is...

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PMID: 30173302
DOI: 10.1007/s00414-018-1927-0

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