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Cytochrome P450 CYP1A2, CYP2C9, CYP2C19 and CYP2D6 genes are not associated with response and remission in a sample of depressive patients.

International clinical psychopharmacology - 1 Sept 2009

Serretti Alessandro, Calati Raffaella, Massat Isabelle, Linotte Sylvie, Kasper Siegfried, Lecrubier Yves, Sens-Espel Roser, Bollen Joseph, Zohar Joseph, Berlo Jacques, Lienard Patricia, De Ronchi Diana, Mendlewicz Julien, Souery Daniel

Abstract excerpt

Cytochrome P450 genes are involved in the metabolism of antidepressants and could influence treatment response. The aim of this study was to investigate the role of allelic variations of the cytochrome P450 CYP1A2, CYP2C9, CYP2C19 and CYP2D6 genes in antidepressant treatment response and remission rates. Two hundred and seventy-eight patients affected by major depression, responders (N = 81) and nonresponders...

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PMID: 19593158
DOI: 10.1097/YIC.0b013e32832e5b0d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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