Article
CYP2D6 ultra-rapid metabolizer phenotype not associated with attempted suicide in a large sample of psychiatric inpatients.
Pharmacogenomics - 1 Aug 2016
Stephens Dustin B, de Leon Jose
Abstract excerpt
AIM: Suicide accounts for over 800,000 deaths per year worldwide and is the tenth-leading cause of mortality in USA. Several studies have investigated cytochrome P450 CYP2D6 ultra-rapid metabolizer (UM) phenotype in relation to suicidality, with mixed results. This study tested the hypothesis of increased suicide risk among CYP2D6 UMs. PATIENTS & METHODS: Among the 4264 state psychiatric hospital inpatients...
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