Article
The Impact of BDNF Polymorphisms on Suicidality in Treatment-Resistant Major Depressive Disorder: A European Multicenter Study.
The international journal of neuropsychopharmacology - 1 Oct 2017
Schosser Alexandra, Carlberg Laura, Calati Raffaella, Serretti Alessandro, Massat Isabel, Spindelegger Christoph, Linotte Sylvie, Mendlewicz Julien, Souery Daniel, Zohar Joseph, Montgomery Stuart, Kasper Siegfried
Abstract excerpt
Background: Numerous studies have reported associations between the brain-derived neurotrophic factor (BDNF) gene and psychiatric disorders, including suicidal behavior, although with conflicting results. Methods: A total of 250 major depressive disorder patients were collected in the context of a European multicenter resistant depression study and treated with antidepressants at adequate doses for at least 4...
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