Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of CYP2C192 and 3 genetic variants with essential hypertension in Koreans.

Yonsei medical journal - 1 Nov 2012

Shin Dong-Jik, Kwon Jisun, Park Ah-Ram, Bae Yousun, Shin Eun-Soon, Park Sungha, Jang Yangsoo

Abstract excerpt

PURPOSE: The cytochrome P450 2C19 (CYP2C19) metabolizes arachidonic acid to produce epoxyicosanoid acids, which are involved in vascular tone and regulation of blood pressure. Recent findings suggest that CYP2C19 gene might be considered as a novel candidate gene for treatment of cardiovascular disease. The aim of the present study was to evaluate the association between two variants, CYP2C19* 2 (681G>A) and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryl Hydrocarbon Hydroxylases
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C19

Share to Homozygote

Share to Hypertension

Share to Logistic Models

Share to Polymorphism, Genetic

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 23074110
DOI: 10.3349/ymj.2012.53.6.1113
PMCID: PMC3481368

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of CYP2C19*2 and *3 genetic variants with essential hypertension in Koreans.PMID 23074110Read ↗

Association of genetic polymorphisms of CYP 2C19 with hypertension in a Chinese Han population.Semantic proximity Read ↗

The contribution of CYP2C gene subfamily involved in epoxygenase pathway of arachidonic acids metabolism to hypertension susceptibility in Russian population.Semantic proximity Read ↗

A Novel Polymorphism of the CYP19 Gene is Associated with Essential Hypertension in China.Semantic proximity Read ↗

Association between cytochrome P450 2C19 polymorphism and clinical outcomes in Chinese patients with coronary artery disease.Semantic proximity Read ↗

Gender specific association of CYP2C9*3 with hyperlipidaemia in Chinese.Semantic proximity Read ↗

Role of CYP2C9 and CYP2C19 polymorphisms in patients with atherosclerosis.Semantic proximity Read ↗

CYP2C19 loss-of-function is associated with increased risk of hypertension in a Hakka population: a case-control study.Semantic proximity Read ↗

Polymorphisms of CYP2C8, CYP2C9 and CYP2C19 and risk of coronary heart disease in Russian population.Semantic proximity Read ↗

Gender-Specific Effect of CYP2C8*3 on the Risk of Essential Hypertension in Bulgarian PatientsSemantic proximity Read ↗

Mutational analysis of CYP2C8 in hypertensive patients using denaturing high performance liquid chromatography.Semantic proximity Read ↗

Single nucleotide polymorphisms in the CYP2J2 and CYP2C8 genes and the risk of hypertension.Semantic proximity Read ↗

Association of interaction between smoking and CYP 2C19*3 polymorphism with coronary artery disease in a Uighur population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.