Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of genetic polymorphisms of CYP 2C19 with hypertension in a Chinese Han population.

Blood pressure - 1 Jun 2011

Ma Yu, Ni Wen, Zhu Wenzhong, Xiong Yuanchang, Deng Xiaoming

Abstract excerpt

OBJECTIVES: Cytochrome P450 (CYP) 2C19 is expressed in vascular endothelium and metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs), which play a centralrole in regulating renal tubular fluid-electrolyte transport and vascular tone. The purpose of this study is to explore the relationship between the genetic polymorphism and hypertension risk in a Chinese Han population. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryl Hydrocarbon Hydroxylases
Share to Asian People
Share to Blood Pressure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C19

Share to DNA Fingerprinting

Share to Hypertension

Share to Linkage Disequilibrium

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 21332417
DOI: 10.3109/08037051.2010.542640

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of genetic polymorphisms of CYP 2C19 with hypertension in a Chinese Han population.PMID 21332417Read ↗

Association of CYP2C19*2 and *3 genetic variants with essential hypertension in Koreans.Semantic proximity Read ↗

CYP4A11 gene T8590C polymorphism is associated with essential hypertension in the male western Chinese Han population.Semantic proximity Read ↗

Single nucleotide polymorphisms in the CYP2J2 and CYP2C8 genes and the risk of hypertension.Semantic proximity Read ↗

A common polymorphism of CYP4A11 is associated with blood pressure in a Chinese population.Semantic proximity Read ↗

A comprehensive study revealed SNP–SNP interactions and a sex-dependent relationship between polymorphisms of the CYP2J2 gene and hypertension riskSemantic proximity Read ↗

The contribution of CYP2C gene subfamily involved in epoxygenase pathway of arachidonic acids metabolism to hypertension susceptibility in Russian population.Semantic proximity Read ↗

Evidence for association of polymorphisms in CYP2J2 and susceptibility to essential hypertension.Semantic proximity Read ↗

The -344C/T polymorphism in the CYP11B2 gene is associated with essential hypertension in the Chinese.Semantic proximity Read ↗

Association between CYP3A5 genotypes with hypertension in Chinese Han population: A case-control study.Semantic proximity Read ↗

CYP2C19 loss-of-function is associated with increased risk of hypertension in a Hakka population: a case-control study.Semantic proximity Read ↗

Genetic determinants of hypertension: A meta-analysis of AGTR1 and CYP11B2 gene polymorphisms.Semantic proximity Read ↗

A haplotype of the CYP4A11 gene associated with essential hypertension in Japanese men.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.