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Article

CYP2C19 loss-of-function is associated with increased risk of hypertension in a Hakka population: a case-control study.

BMC cardiovascular disorders - 6 Apr 2023

Cai Nan, Li Cunren, Gu Xianfang, Zeng Wenfeng, Zhong Jiawei, Liu Jingfeng, Zeng Guopeng, Zhu Junxing, Hong Haifeng

Abstract excerpt

BACKGROUND: Genetic factors have a certain proportion in the risk factors of hypertension. The purpose was to investigate the relationship of cytochrome P450 2C19 (CYP2C19) polymorphisms with hypertension in Hakka population. METHODS: The study included 1,872 hypertensive patients and 1,110 controls. The genotypes of CYP2C19 rs4244285 and rs4986893 of all individuals were detected and analyzed. RESULTS: The...

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PMID: 37024851
DOI: 10.1186/s12872-023-03207-w
PMCID: PMC10080785

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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