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Article

A functional promoter polymorphism of the human IL18 gene is associated with aspirin-induced urticaria.

The British journal of dermatology - 1 Nov 2011

Kim S-H, Son J K, Yang E-M, Kim J-E, Park H-S

Abstract excerpt

BACKGROUND: Urticaria is the commonest cutaneous reaction caused by aspirin or other nonsteroidal anti-inflammatory drugs. The pathogenesis of aspirin-induced urticaria (AIU) is not fully understood, but appears to involve mast cell activation and neutrophil infiltration. OBJECTIVES: To investigate the genetic contribution of interleukin (IL)-18, which can amplify acute inflammation by promoting mast cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21692767
DOI: 10.1111/j.1365-2133.2011.10467.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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