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Article

Interleukin 18 (IL18) gene promoter polymorphisms are associated with type 1 diabetes mellitus in Brazilian patients.

Cytokine - 1 May 2013

Tavares Nathália A C, Santos Manuella M S, Moura Ronald, Araújo Jacqueline, Guimarães Rafael, Crovella Sergio, Brandão Lucas

Abstract excerpt

Interleukin 18 (IL-18) is a cytokine that plays an important role in the Th1 response, by its ability to induce IFN-γ production in T cells and natural killer cells. Functional variants of IL18 gene has been reported as associated with type 1 diabetes (T1D). In the present study were analyzed three promoter single nucleotide polymorphisms (SNPs), at -656 (rs1946519), -607 (rs1946518) and -137 (rs187238) position,...

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Source

Identifiers

PMID: 23557801
DOI: 10.1016/j.cyto.2013.03.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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