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Article

Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting.

Developmental cell - 1 Aug 2002

Babst Markus, Katzmann David J, Estepa-Sabal Eden J, Meerloo Timo, Emr Scott D

Abstract excerpt

The sorting of transmembrane proteins (e.g., cell surface receptors) into the multivesicular body (MVB) pathway to the lysosomal/vacuolar lumen requires the function of the ESCRT protein complexes. The soluble coiled-coil-containing proteins Vps2, Vps20, Vps24, and Snf7 are recruited from the cytoplasm to endosomal membranes where they oligomerize into a protein complex, ESCRT-III. ESCRT-III contains two...

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PMID: 12194857
DOI: 10.1016/s1534-5807(02)00220-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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