A simulation study to assess a variable selection method for selecting single nucleotide polymorphisms associated with disease.

Abstract excerpt

In genome-wide association studies, where hundreds of thousands of single nucleotide polymorphisms (SNPs) are genotyped, the potential for false positives is high and methods for selecting models with only a few SNPs are required. Methods for variable selection giving sets of SNPs associated with disease have been developed, but are still less common than evaluation of individual SNPs one at a time. To assess the...

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