Article
Selection of single-nucleotide polymorphisms in disease association data.
BMC genetics - 30 Dec 2005
Joo Jungnam, Tian Xin, Zheng Gang, Lin Jing-Ping, Geller Nancy L
Abstract excerpt
We studied several methods for selecting single-nucleotide polymorphisms (SNPs) in a disease association study. Two major categories for analytical strategy are the univariate and the set selection approaches. The univariate approach evaluates each SNP marker one at a time, while the set selection approach tests disease association of a set of SNP markers simultaneously. We examined various test statistics that...
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