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Article

The N-terminal region of IFITM3 modulates its antiviral activity by regulating IFITM3 cellular localization.

Journal of virology - 1 Dec 2012

Jia Rui, Pan Qinghua, Ding Shilei, Rong Liwei, Liu Shan-Lu, Geng Yunqi, Qiao Wentao, Liang Chen

Abstract excerpt

Interferon-inducible transmembrane (IFITM) protein family members IFITM1, -2, and -3 restrict the infection of multiple enveloped viruses. Significant enrichment of a minor IFITM3 allele was recently reported for patients who were hospitalized for seasonal and 2009 H1N1 pandemic flu. This IFITM3...

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Source

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Identifiers

PMID: 23055554
DOI: 10.1128/JVI.01828-12
PMCID: PMC3503121

Genes

IFITM3
IFITM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23055554-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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