Article
New single nucleotide polymorphisms associated with differences in platelets reactivity in patients with type 2 diabetes treated with acetylsalicylic acid: genome-wide association approach and pooled DNA strategy.
Journal of thrombosis and thrombolysis - 1 Jul 2013
Postula Marek, Janicki Piotr K, Rosiak Marek, Kaplon-Cieslicka Agnieszka, Trzepla Ewa, Filipiak Krzysztof J, Kosior Dariusz A, Czlonkowski Andrzej, Opolski Grzegorz
Abstract excerpt
The objective of this study was to use genome-wide association approach and pooled DNA strategy to search for new genomic loci associated with inter-individual differences in platelet reactivity in the diabetic patients during acetylsalicylic acid (ASA) treatment. Study cohort consisted of 297 diabetic patients who had been taking ASA (75 mg daily) for at least 3 months. We tested association of single nucleotide...
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