Article
Lack of effect of common single nucleotide polymorphisms in leukotriene pathway genes on platelet reactivity in patients with diabetes.
Molecular medicine reports - 1 Sept 2013
Rosiak Marek, Postula Marek, Kaplon-Cieslicka Agnieszka, Kondracka Agnieszka, Trzepla Ewa, Zaremba Malgorzata, Filipiak Krzysztof J, Kosior Dariusz A, Czlonkowski Andrzej, Opolski Grzegorz, Janicki Piotr K
Abstract excerpt
The aim of the present study was to investigate the effect of genetic polymorphisms in candidate genes within the leukotriene (LT) pathway on platelet reactivity and the concentration of selected LTs in diabetic patients treated with acetylsalicylic acid (ASA). The study cohort consisted of 287 Caucasians with type 2 diabetes who had received treatment with ASA tablets (75 mg/day) for at least three months....
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