Article
Myosin VI has a one track mind versus myosin Va when moving on actin bundles or at an intersection.
Traffic (Copenhagen, Denmark) - 1 Jan 2013
Ali M Yusuf, Previs Samantha B, Trybus Kathleen M, Sweeney H Lee, Warshaw David M
Abstract excerpt
Myosin VI (myoVI) and myosin Va (myoVa) serve roles both as intracellular cargo transporters and tethers/anchors. In both capacities, these motors bind to and processively travel along the actin cytoskeleton, a network of intersecting actin filaments and bundles that present directional challenges to these motors. Are myoVI and myoVa inherently different in their abilities to interact and maneuver through the...
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