Article
Functional multiplicity of motor molecules revealed by a simple kinetic analysis.
Biophysical journal - 1 Sept 1994
Lark E, Omoto C K, Schumaker M F
Abstract excerpt
We present a simple analytical solution for a kinetic model of motor molecule function with multiple arms. This model has a rate of motion proportional to the probability that all arms in a complex are detached from the cytoskeleton and, therefore, we refer to it as obligate cooperativity. The model has the form: v = Vmax/(1 + q/S)n, where Vmax is the maximum velocity, the product nq is the effective Michaelis...
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