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Article

Neck length and processivity of myosin V.

The Journal of biological chemistry - 1 Aug 2003

Sakamoto Takeshi, Wang Fei, Schmitz Stephan, Xu Yuhui, Xu Qian, Molloy Justin E, Veigel Claudia, Sellers James R

Abstract excerpt

Myosin V is an unconventional myosin that transports cargo such as vesicles, melanosomes, or mRNA on actin filaments. It is a two-headed myosin with an unusually long neck that has six IQ motifs complexed with calmodulin. In vitro studies have shown that myosin V moves processively on actin, taking multiple 36-nm steps that coincide with the helical repeat of actin. This allows the molecule to "walk" across the...

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Identifiers

PMID: 12740393
DOI: 10.1074/jbc.M303662200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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