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Article

Microtubule-dependent balanced cell contraction and luminal-matrix modification accelerate epithelial tube fusion.

Nature communications - 12 Apr 2016

Kato Kagayaki, Dong Bo, Wada Housei, Tanaka-Matakatsu Miho, Yagi Yoshimasa, Hayashi Shigeo

Abstract excerpt

Connection of tubules into larger networks is the key process for the development of circulatory systems. In Drosophila development, tip cells of the tracheal system lead the migration of each branch and connect tubules by adhering to each other and simultaneously changing into a torus-shape. We show that as adhesion sites form between fusion cells, myosin and microtubules form polarized bundles that connect the...

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Identifiers

PMID: 27067650
DOI: 10.1038/ncomms11141
PMCID: PMC4832058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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