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Article

Identification of POMC exonic variants associated with substance dependence and body mass index.

PloS one - 1 Jan 2012

Wang Fan, Gelernter Joel, Kranzler Henry R, Zhang Huiping

Abstract excerpt

BACKGROUND: Risk of substance dependence (SD) and obesity has been linked to the function of melanocortin peptides encoded by the proopiomelanocortin gene (POMC). METHODS AND RESULTS: POMC exons were Sanger sequenced in 280 African Americans (AAs) and 308 European Americans (EAs). Among them, 311 (167 AAs and 114 EAs) were affected with substance (alcohol, cocaine, opioid and/or marijuana) dependence and 277 (113...

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Source

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Identifiers

PMID: 23028917
DOI: 10.1371/journal.pone.0045300
PMCID: PMC3444488

Genes

POMC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of POMC exonic variants associated with substance dependence and body mass index.PMID 23028917Read ↗

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