Article
Intrathymic T cell repertoire after prenatal trinitrobenzene-sulfonic acid-treatment.
Cellular immunology - 1 Mar 1990
Zöller M
Abstract excerpt
It is still a matter of debate, whether tolerance toward self-non-MHC antigens is due to intrathymic deletion or to regulatory processes in the periphery. To further pursue this question, responsiveness toward TNP and an anti-TNP monoclonal antibody (Sp6) carrying a recurrent idiotype was evaluated in prenatally trinitrobenzenesulfonic acid (TNBS)-treated mice. In prenatally untreated as well as in TNBS-treated...
Topics
- Animals
- Antigens
- Female
- Fetus
- Histocompatibility Antigens
- Immune Tolerance
- Immunoglobulin Idiotypes
- Lymphocyte Activation
- Mice
- Mice, Inbred BALB C
- Nitrobenzenes
- Phenotype
