Increased frequency of 2,4,6-trinitrophenyl (TNP)-specific, H-2b-restricted cytotoxic T lymphocyte precursors in transgenic mice expressing a T cell receptor beta chain gene from an H-2b-restricted, TNP-specific cytolytic T cell clone.

doi:10.1002/eji.1830220208

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Article

Increased frequency of 2,4,6-trinitrophenyl (TNP)-specific, H-2b-restricted cytotoxic T lymphocyte precursors in transgenic mice expressing a T cell receptor beta chain gene from an H-2b-restricted, TNP-specific cytolytic T cell clone.

European journal of immunology - 1 Feb 1992

Iglesias A, Hansen-Hagge T, Von Bonin A, Weltzien H U

Abstract excerpt

T cell antigen receptors (TcR) expressing V alpha 10/J alpha BBM142 genes in association with beta chains containing J beta 2.6 elements were found to be predominant among 2,4,6-trinitrophenyl (TNP)-specific, H-2b-restricted cytolytic T cell lines (CTL). To assess the relative contribution of the TcR beta chain to the TNP specificity as well as to the selection of the respective TcR alpha chain elements we...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor
Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
Genes
H-2 Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Transgenic

Molecular Sequence Data

Oligodeoxyribonucleotides

Polymerase Chain Reaction

Receptors, Antigen, T-Cell, alpha-beta

T-Lymphocytes, Cytotoxic

Trinitrobenzenes

Source

Open in PubMed

Identifiers

PMID: 1311259
DOI: 10.1002/eji.1830220208

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1311259-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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