The genetics of scleroderma: looking into the postgenomic era.

Abstract excerpt

PURPOSE OF REVIEW: The last decade has seen enormous progress in understanding genetic associations of systemic sclerosis to explain the observed heritability. This review highlights the most recent findings and places them in the context of proposed functional roles. RECENT FINDINGS: Over 30 genes and gene regions have now been identified as scleroderma susceptibility loci. These include both human leukocyte...

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