Article
Genetics of scleroderma: implications for personalized medicine?
BMC medicine - 11 Jan 2013
Assassi Shervin, Radstake Timothy R D J, Mayes Maureen D, Martin Javier
Abstract excerpt
Significant advances have been made in understanding the genetic basis of systemic sclerosis (scleroderma) in recent years. Can these discoveries lead to individualized monitoring and treatment? Besides robustly replicated genetic susceptibility loci, several genes have been recently linked to various systemic sclerosis disease manifestations. Furthermore, inclusion of genetic studies in design and analysis of...
Topics
- Genetic Markers
- Genetic Predisposition to Disease
- Humans
- Precision Medicine
- Scleroderma, Systemic