Article
Immunogenetics of Systemic Sclerosis.
Genes - 5 May 2024
Gumkowska-Sroka Olga, Kotyla Kacper, Kotyla Przemysław
Abstract excerpt
Systemic sclerosis (SSc) is a rare autoimmune connective tissue disorder characterized by massive fibrosis, vascular damage, and immune imbalance. Advances in rheumatology and immunology over the past two decades have led to a redefinition of systemic sclerosis, shifting from its initial perception as primarily a "hyperfibrotic" state towards a recognition of systemic sclerosis as an immune-mediated disease....
Topics
- Scleroderma, Systemic
- Humans
- Immunogenetics
- Genetic Predisposition to Disease
