Article
The genetics of systemic sclerosis: an update.
Clinical and experimental rheumatology - 1 Jan 2000
Romano Eloisa, Manetti Mirko, Guiducci Serena, Ceccarelli Claudia, Allanore Yannick, Matucci-Cerinic Marco
Abstract excerpt
Systemic sclerosis (SSc) is a complex systemic disease characterised by fibrosis of the skin and internal organs, vasculopathy, and activation of the immune system. The complex pathophysiology of SSc implies the potential involvement of 'culprit' genes, either individually or, more likely, together, in driving the disease process. Most of the studies that have provided evidence for the contribution of various...
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