Article
The genetics of scleroderma.
Current rheumatology reports - 1 Feb 2011
Martin Javier, Fonseca Carmen
Abstract excerpt
The importance of the genetic component in the pathogenesis of scleroderma, or systemic sclerosis, has been strengthened in the past 2 years with studies on genetic markers-either candidate gene or genome-wide association studies--in large case-control series. Multiple genes have been consistently associated with susceptibility to scleroderma, and interestingly, several of them are involved in immune regulation....
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