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Article

Identification of genetic variants in base excision repair pathway and their associations with risk of esophageal squamous cell carcinoma.

Cancer research - 15 Jun 2004

Hao Bingtao, Wang Haijian, Zhou Kaixin, Li Yi, Chen Xiaoping, Zhou Gangqiao, Zhu Yunping, Miao Xiaoping, Tan Wen, Wei Qingyi, Lin Dongxin, He Fuchu

Abstract excerpt

The etiology of esophageal squamous cell carcinoma (ESCC) has been shown to be associated with genetic and certain environmental factors that produce DNA damage. Base excision repair (BER) genes are responsible for repair of DNA damage caused by reactive oxygen species and other electrophiles and therefore are good candidate susceptibility genes for ESCC. We first screened eight BER genes for new and potential...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15205355
DOI: 10.1158/0008-5472.CAN-04-0372

Genes

XRCC1
LIG3
MBD4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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