Article
The association of APE1 -656T > G and 1349 T > G polymorphisms and cancer risk: a meta-analysis based on 37 case-control studies.
BMC cancer - 18 Dec 2011
Zhou Bin, Shan Hailin, Su Ying, Xia Kai, Shao Xiaxia, Mao Weidong, Shao Qing
Abstract excerpt
BACKGROUND: APE1 (apurinic/apyrimidinic endonuclease 1) is an important DNA repair protein in the base excision repair pathway. Polymorphisms in APE1 have been implicated in susceptibility to cancer; however, results from the published studies remained inconclusive. The objective of this study was to conduct a meta-analysis investigating the association between polymorphisms in APE1 and the risk for cancer....
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