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Article

Genetic polymorphism of DNA base-excision repair genes (APE1, OGG1 and XRCC1) and their correlation with risk of lung cancer in a Chinese population.

Archives of medical research - 1 Apr 2011

Li Zheng, Guan Wei, Li Meng-xia, Zhong Zhao-yang, Qian Cheng-yuan, Yang Xue-qin, Liao Ling, Li Zeng-peng, Wang Dong

Abstract excerpt

BACKGROUND AND AIMS: Reactive oxygen species (ROS) and numerous carcinogens may cause DNA damage including oxidative base lesions that contribute to the risk of lung cancer. The base excision repair (BER) pathway could effectively remove oxidative lesions in which 8-oxoguanine glycosylase-1 (OGG1), x-ray repair cross-complementing 1 (XRCC1), and apurinic/apyimidinic endonuclease 1 (APE1) play key roles. The aim...

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Source

Identifiers

PMID: 21722819
DOI: 10.1016/j.arcmed.2011.04.005

Genes

XRCC1
OGG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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