Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The A3 allele of the HLA-DQA1 locus is associated with susceptibility to type 1 diabetes in Japanese.

Proceedings of the National Academy of Sciences of the United States of America - 1 Feb 1990

Todd J A, Fukui Y, Kitagawa T, Sasazuki T

Abstract excerpt

Analysis of the frequencies of class II HLA-DR and HLA-DQ alleles by serological and DNA typing in 49 Japanese patients with type 1 (insulin-dependent) diabetes and 31 Japanese controls indicates the following. (i) Susceptibility is more strongly associated with the HLA-DQ subregion than with the HLA-DR subregion. (ii) Of the class II alleles detected, the A3 allele of the DQA1 locus was the most strongly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Base Sequence
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Haplotypes

Share to Molecular Sequence Data

Share to Oligonucleotide Probes

Share to Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 2300572
DOI: 10.1073/pnas.87.3.1094
PMCID: PMC53417

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The A3 allele of the HLA-DQA1 locus is associated with susceptibility to type 1 diabetes in Japanese.PMID 2300572Read ↗

Genetic analysis of HLA class II alleles and susceptibility to type 1 (insulin-dependent) diabetes mellitus in Japanese subjects.Semantic proximity Read ↗

An investigation of Japanese subjects maps susceptibility to type 1 (insulin-dependent) diabetes mellitus close to the DQA1 gene.Semantic proximity Read ↗

HLA and non-HLA genetic factors in Japanese IDDM.Semantic proximity Read ↗

HLA-class II and class I genotypes among Japanese children with Type 1A diabetes and their families.Semantic proximity Read ↗

Asian-specific HLA haplotypes reveal heterogeneity of the contribution of HLA-DR and -DQ haplotypes to susceptibility to type 1 diabetes.Semantic proximity Read ↗

HLA class II (DR, DQ) in Japanese patients with type 1 diabetes mellitus.Semantic proximity Read ↗

Clinical and Genetic Characteristics of Autoimmune Polyglandular Syndrome Type 3 Variant in the Japanese PopulationSemantic proximity Read ↗

Genetics of type 1 diabetes in Asian and Caucasian populations.Semantic proximity Read ↗

HLA-DQA and DQB alleles contribute to susceptibility to insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Analysis by the polymerase chain reaction of histocompatibility leucocyte antigen-DR9-linked susceptibility to insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Genetic susceptibility of childhood type 1 diabetes mellitus in Japan.Semantic proximity Read ↗

Particular HLA-DQ alpha beta heterodimer associated with IDDM susceptibility in both DR4-DQw4 Japanese and DR4-DQw8/DRw8-DQw4 whites.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.