HLA and non-HLA genetic factors in Japanese IDDM.

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Article

HLA and non-HLA genetic factors in Japanese IDDM.

[Hokkaido igaku zasshi] The Hokkaido journal of medical science - 1 Nov 1991

Aparicio J M

Abstract excerpt

The HLA of 56 unrelated Japanese with insulin-dependent diabetes mellitus (IDDM) was investigated and reconfirmed their role in the pathogenesis by restriction fragment length polymorphism (RFLP). DQw4 showed the highest correlation to IDDM not only within the DQ system but among all the antigens, suggesting that HLA-DQ might play the most important role in the development of IDDM similar as in Caucasians. When...

Topics

Adolescent
Adult
Alleles
Asian People
Base Sequence
Child
Child, Preschool
Chromosomes, Human, Pair 11
Diabetes Mellitus, Type 1
Female
HLA-DQ Antigens
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Japan

Male

Molecular Sequence Data

Polymerase Chain Reaction

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 1686010

Genes

ETS1
INS
THY1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1686010-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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