Article
HLA-class II and class I genotypes among Japanese children with Type 1A diabetes and their families.
Pediatric diabetes - 1 Feb 2012
Sugihara Shigetaka, Ogata Tsutomu, Kawamura Tomoyuki, Urakami Tatsuhiko, Takemoto Koji, Kikuchi Nobuyuki, Takubo Noriyuki, Tsubouchi Kohji, Horikawa Reiko, Kobayashi Kisho, Kasahara Yoshihito, Kikuchi Tohru, Koike Akemi, Mochizuki Takahiro, Minamitani Kanshi, Takaya Ryuzo, Mochizuki Hiroshi, Nishii Aki, Yokota Ichiro, Kizaki Zenro, Mori Tetsuo, Shimura Naoto, Mukai Tokuo, Matsuura Nobuo, Fujisawa Takao, Ihara Kenji, Kosaka Kitaro, Kizu Rika, Takahashi Toshikazu, Matsuo Satoshi, Hanaki Keiichi, Igarashi Yutaka, Sasaki Goro, Soneda Shun, Teno Shinichi, Kanzaki Susumu, Saji Hiroh, Tokunaga Katsushi, Amemiya Shin
Abstract excerpt
OBJECTIVE: To determine the HLA-DRB1, DQB1, DPB1, A, C, and B genotypes among Japanese children with autoimmune type 1 diabetes. METHODS: Four hundred and thirty patients who were GADAb and/or IA-2Ab-positive (Type 1A) were recruited from 37 medical centers as part of a nationwide multicenter collaborative study. DNA samples from 83 siblings of the children with Type 1A diabetes and 149 parent-child trios were...
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