Article
Asian-specific HLA haplotypes reveal heterogeneity of the contribution of HLA-DR and -DQ haplotypes to susceptibility to type 1 diabetes.
Diabetes - 1 Feb 2002
Kawabata Yumiko, Ikegami Hiroshi, Kawaguchi Yoshihiko, Fujisawa Tomomi, Shintani Maki, Ono Masaya, Nishino Masanori, Uchigata Yasuko, Lee Inkyu, Ogihara Toshio
Abstract excerpt
To assess the effect of Asian-specific HLA haplotypes on susceptibility to type 1 diabetes, we investigated the association of genotypic combinations of DRB1-DQB1 haplotypes with susceptibility to type 1 diabetes. We studied 132 Japanese patients with type 1 diabetes and 157 control subjects, along with 67 Korean patients and 109 control subjects. DRB1*0405-DQB1*0401 and DRB1*0901-DQB1*0303 were confirmed to be...
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