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Article

HLA class II (DR, DQ) in Japanese patients with type 1 diabetes mellitus.

Acta paediatrica Japonica : Overseas edition - 1 Dec 1990

Tanaka M, Abe J, Ito J, Horikawa R, Miki Y, Nakayama M, Kohsaka T, Tanae A, Hibi I

Abstract excerpt

DNA restriction fragment length polymorphism (RFLP) typing of HLA-DR and DQ alleles of 60 Japanese type 1 (insulin dependent) diabetic patients and 115 controls was performed. RFLP typing of DRB1 showed increased frequency of DR9 and decreased frequencies of DR2 and DRW6 among patients compared to controls. In the RFLP typing of BamHI-digested DNA to DQ beta probe (BamHI-DQB1), the incidence of the 10.26 kb...

Topics

Alleles
Diabetes Mellitus, Type 1
HLA-DQ Antigens
HLA-DR Antigens
Haplotypes
Humans
Japan
Polymorphism, Restriction Fragment Length

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1982037
DOI: 10.1111/j.1442-200x.1990.tb00898.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1982037-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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