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Article

Common variants in the sex hormone-binding globulin gene (SHBG) and polycystic ovary syndrome (PCOS) in Mediterranean women.

Human reproduction (Oxford, England) - 1 Dec 2012

Martínez-García M Ángeles, Gambineri Alessandra, Alpañés Macarena, Sanchón Raúl, Pasquali Renato, Escobar-Morreale Héctor F

Abstract excerpt

STUDY QUESTION: Is there an association between polycystic ovary syndrome (PCOS) and the sex hormone-binding globulin (SHBG) rs1799941, rs6257, rs6259 and rs727428 variants in a large series of Mediterranean women? SUMMARY ANSWER: The rs727428 and rs6259 variants are associated with PCOS in Mediterranean women. WHAT IS KNOWN ALREADY: The level of SHBG, the primary plasma transport protein for sex steroids, which...

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Source

Identifiers

PMID: 23001781
DOI: 10.1093/humrep/des335

Genes

SHBG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Common variants in the sex hormone-binding globulin gene (SHBG) and polycystic ovary syndrome (PCOS) in Mediterranean women.PMID 23001781Read ↗

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Association of the Genetic Polymorphisms rs6259 and rs727428 of the SHBG Gene with Polycystic Ovary Syndrome Risk: A Meta-Analysis.Semantic proximity Read ↗

Polymorphisms in the SHBG gene influence serum SHBG levels in women with polycystic ovary syndrome.Semantic proximity Read ↗

Sex hormone-binding globulin genetic variation: associations with type 2 diabetes mellitus and polycystic ovary syndrome.Semantic proximity Read ↗

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