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Article

Association between human SHBG gene polymorphisms and risk of PCOS: a meta-analysis.

Reproductive biomedicine online - 1 Jan 2021

Li Yuxi, Fang Lanlan, Yan Yang, Wang Zhen, Wu Ze, Jia Qiongqiong, Cheng Jung-Chien, Sun Ying-Pu

Abstract excerpt

Sex hormone-binding globulin (SHBG) is a plasma glycoprotein that binds androgens and oestrogens, and regulates their bioavailability to target tissues. To date, several human SHBG gene polymorphisms have been identified. Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders, and hyperandrogenism has been considered to be a hallmark of PCOS. Many studies have examined the association...

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Identifiers

PMID: 33168491
DOI: 10.1016/j.rbmo.2020.10.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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