Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ovarian cancer risk and common variation in the sex hormone-binding globulin gene: a population-based case-control study.

BMC cancer - 5 Apr 2007

Garcia-Closas Montserrat, Brinton Louise A, Lissowska Jolanta, Richesson Douglas, Sherman Mark E, Szeszenia-Dabrowska Neonila, Peplonska Beata, Welch Robert, Yeager Meredith, Zatonski Witold, Chanock Stephen J

Abstract excerpt

BACKGROUND: The sex hormone-binding globulin (SHBG) is a carrier protein that modulates the bio-availability of serum sex steroid hormones, which may be involved in ovarian cancer. We evaluated whether common genetic variation in SHBG and its 3' neighbor ATP1B2, in linkage disequilibrium, is associated with the risk of epithelial ovarian cancer. METHODS: The study population included 264 women with ovarian...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cation Transport Proteins

Share to Cell Adhesion Molecules, Neuronal

Share to Genetics, Population

Share to Ovarian Neoplasms

Share to Sex Hormone-Binding Globulin

Source

Open in PubMed Open full text

Identifiers

PMID: 17411440
DOI: 10.1186/1471-2407-7-60
PMCID: PMC1855931

Genes

SHBG

Variants

rs6259

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ovarian cancer risk and common variation in the sex hormone-binding globulin gene: a population-based case-control study.PMID 17411440Read ↗

Decreased risk of ovarian cancer associated with rs9898876 sex hormone-binding globulin gene variant.Semantic proximity Read ↗

Decreased Risk of Ovarian Cancer Associated With rs9898876 Sex Hormone-binding Globulin Gene VariantSemantic proximity Read ↗

Identification of common variants in the SHBG gene affecting sex hormone-binding globulin levels and breast cancer risk in postmenopausal women.Semantic proximity Read ↗

Common Variants in the Sex Hormone-Binding Globulin (SHBG) Gene Influence SHBG Levels in Women with Polycystic Ovary Syndrome.Semantic proximity Read ↗

Common variants in the sex hormone-binding globulin gene (SHBG) and polycystic ovary syndrome (PCOS) in Mediterranean women.Semantic proximity Read ↗

Association between human SHBG gene polymorphisms and risk of PCOS: a meta-analysis.Semantic proximity Read ↗

Association of the Genetic Polymorphisms rs6259 and rs727428 of the SHBG Gene with Polycystic Ovary Syndrome Risk: A Meta-Analysis.Semantic proximity Read ↗

Genetic polymorphisms are associated with serum levels of sex hormone binding globulin in postmenopausal women.Semantic proximity Read ↗

Sex hormone-binding globulin polymorphisms in familial and sporadic breast cancer.Semantic proximity Read ↗

Association between SHBG Asp327Asn (rs6259) polymorphism and breast cancer risk: a meta-analysis of 10,454 cases and 13,111 controls.Semantic proximity Read ↗

Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium.Semantic proximity Read ↗

Association of ERBB4 and SHBG gene polymorphisms with polycystic ovarian syndrome in South Indian women: a case-control genetic analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.