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Article

Association of a single nucleotide polymorphism of the NPR3 gene promoter with early onset ischemic stroke in an Italian cohort.

European journal of internal medicine - 1 Jan 2013

Rubattu Speranza, Giusti Betti, Lotta Luca Andrea, Peyvandi Flora, Cotugno Maria, Stanzione Rosita, Marchitti Simona, Palombella Anna Maria, Di Castro Sara, Rasura Maurizia, Mannucci Pier Mannuccio, Volpe Massimo

Abstract excerpt

BACKGROUND: NPR3, located on human chromosome 5 (5p14-p13), encodes the natriuretic peptide receptor type C (NPR-C) that is mainly known as the natriuretic peptide clearance receptor. Involvement of NPR3 in susceptibility to cardiovascular diseases, i.e. hypertension, has been previously shown. With regard to stroke predisposition, evidence for a potential role of genetic variation within or nearby NPR3 has been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Atrial Natriuretic Factor

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Source

Identifiers

PMID: 22995222
DOI: 10.1016/j.ejim.2012.09.002

Genes

NPR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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