Article
A novel missense mutation of exon 3 in the type A human natriuretic peptide receptor gene: possible association with essential hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 May 2002
Nakayama Tomohiro, Soma Masayoshi, Mizutani Yoshihiro, Xinjuan Xu, Honye Junko, Kaneko Yukie, Rahmutula Dolkun, Aoi Noriko, Kosuge Kotoko, Saito Satoshi, Ozawa Yukio, Kanmatsuse Katsuo, Kokubun Shinichiro
Abstract excerpt
The natriuretic peptide (NP) family is involved in regulation of blood pressure and fluid volume. We recently characterized the exon/intron organization of the human type A NP receptor (hNPRA) gene. The aim of this study was to isolate the genetic markers according to the organization of this gene, and to study the association between this gene and essential hypertension. Using polymerase chain reaction-single...
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