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Article

Allelic variants of natriuretic peptide receptor genes are associated with family history of hypertension and cardiovascular phenotype.

Journal of hypertension - 1 Aug 2003

Pitzalis Maria Vittoria, Sarzani Riccardo, Dessì-Fulgheri Paolo, Iacoviello Massimo, Forleo Cinzia, Lucarelli Katya, Pietrucci Francesca, Salvi Fabio, Sorrentino Sandro, Romito Roberta, Guida Pietro, Rappelli Alessandro, Rizzon Paolo

Abstract excerpt

OBJECTIVE: Abnormalities in the natriuretic peptide system could play a key role in the genesis of hypertension. We evaluated the associations between a family history of hypertension, cardiovascular phenotype and allelic variants of Npr1 and Npr3, two candidate genes that codify for natriuretic peptide receptors. METHODS: We genotyped 45 young normotensive subjects (19 males, 26.8 +/- 3.7 years) with accurately...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12872042
DOI: 10.1097/00004872-200308000-00012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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