Article
The glu298asp polymorphism in the nitric oxide synthase 3 gene is associated with the risk of ischemic stroke in two large independent case-control studies.
Human genetics - 1 Apr 2007
Berger Klaus, Stögbauer Florian, Stoll Monika, Wellmann Juergen, Huge Andreas, Cheng Suzanne, Kessler Christof, John Ulrich, Assmann Gerd, Ringelstein E Bernd, Funke Harald
Abstract excerpt
The search for genes involved in the pathogenesis of stroke has been highlighted as a field of needs. We followed the concept, that stroke represents a complex genetic disorder, and analyzed the contribution of 106 informative single nucleotide polymorphisms (SNPs) from 63 candidate genes for cardiovascular diseases for the risk of stroke. We conducted two independent case-control studies in two different German...
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