Article
9p21.3 risk locus is associated with first-ever myocardial infarction in an Austrian cohort.
Journal of cardiovascular medicine (Hagerstown, Md.) - 1 Aug 2016
Haslacher Helmuth, Perkmann Thomas, Ratzinger Franz, Grimm Gabriele, Exner Markus, Keller Alexandra, Schmetterer Klaus, Priemer Clemens, Endler Georg, Wagner Oswald, Schillinger Martin
Abstract excerpt
AIMS: Atherosclerosis often presents as a complex systemic disease that is strongly influenced by lifestyle factors, but also by the genetic background. The sequence variant rs1333049 affects the expression of ANRIL, a noncoding RNA transcript playing a key role in the regulation of inflammatory processes. We thus aimed to replicate the predictive value of genetic information on this variant regarding the...
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