Article
Genome-wide analysis of blood pressure variability and ischemic stroke.
Stroke - 1 Oct 2013
Yadav Sunaina, Cotlarciuc Ioana, Munroe Patricia B, Khan Muhammad S, Nalls Michael A, Bevan Steve, Cheng Yu-Ching, Chen Wei-Min, Malik Rainer, McCarthy Nina S, Holliday Elizabeth G, Speed Douglas, Hasan Nazeeha, Pucek Mateusz, Rinne Paul E, Sever Peter, Stanton Alice, Shields Denis C, Maguire Jane M, McEvoy Mark, Scott Rodney J, Ferrucci Luigi, Macleod Mary J, Attia John, Markus Hugh S, Sale Michele M, Worrall Bradford B, Mitchell Braxton D, Dichgans Martin, Sudlow Cathy, Meschia James F, Rothwell Peter M, Caulfield Mark, Sharma Pankaj
Abstract excerpt
BACKGROUND AND PURPOSE: Visit-to-visit variability in blood pressure (vBP) is associated with ischemic stroke. We sought to determine whether such variability has genetic causes and whether genetic variants associated with BP variability are also associated with ischemic stroke. METHODS: A Genome Wide Association Study (GWAS) for loci influencing BP variability was undertaken in 3802 individuals from the...
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