Article
Prognostic impact of VEGFA germline polymorphisms in patients with HER2-positive primary breast cancer.
Anticancer research - 1 Sept 2012
Maae Else, Andersen Rikke Fredslund, Steffensen Karina Dahl, Jakobsen Erik Hugger, Brandslund Ivan, Sørensen Flemming Brandt, Jakobsen Anders
Abstract excerpt
BACKGROUND: Vascular endothelial growth factor A (VEGFA) is essential in tumour angiogenesis, and polymorphisms in the VEGFA gene have been associated with breast cancer prognosis. The human epidermal growth factor receptor 2 (HER2) is overexpressed in breast tumours and is also associated with angiogenesis. We investigated the possible prognostic impact of VEGFA single nucleotide polymorphisms (SNPs) in patients...
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