Article
Vascular endothelial growth factor ‑634G/C polymorphism is associated with increased breast cancer risk and aggressiveness.
Molecular medicine reports - 1 Oct 2013
Sa-Nguanraksa Doonyapat, Chuangsuwanich Tuenjai, Pongpruttipan Tawatchai, Kummalue Tanawan, Rojananin Supakorn, Ratanawichhitrasin Adune, Prasarttong-Osoth Poramaporn, Chuthatisith Suebwong, Pisarnturakit Pongthep, Aeumrithaicharoenchok Waraporn, Rushatamukayanunt Pradit, Lohsiriwat Visnu, Boonsripitayanon Mongkol, Malasit Prida, O-Charoenrat Pornchai
Abstract excerpt
Polymorphisms in the promoter and 5' untranslated region of vascular endothelial growth factor (VEGF) have been associated with VEGF levels. To investigate the role of VEGF polymorphisms in breast cancer, the VEGF ‑2578C/A, ‑1498C/T, ‑1154G/A and ‑634G/C polymorphisms were genotyped in 483 breast...
Topics
- Adult
- Breast Neoplasms
- Carcinoma, Ductal, Breast
- Case-Control Studies
- Disease-Free Survival
- Female
- Gene Expression
- Gene Frequency
- Genetic Association Studies