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Article

The role of vascular endothelial growth factor a polymorphisms in breast cancer.

International journal of molecular sciences - 13 Nov 2012

Sa-Nguanraksa Doonyapat, O-Charoenrat Pornchai

Abstract excerpt

Breast cancer is the most common cancer in females and the leading cause of cancer death in women worldwide. Angiogenesis, the formation of new blood vessels, plays an important role in the development and progression of breast cancer. Vascular endothelial growth factor A (VEGFA), the key modulator of angiogenesis, is highly expressed in cancer tissue and correlates with its more aggressive features....

Topics

Animals
Breast Neoplasms
Disease Progression
Female
Gene Expression Regulation, Neoplastic
Genetic Predisposition to Disease
Humans
Molecular Targeted Therapy
Neovascularization, Pathologic
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Risk

Vascular Endothelial Growth Factor A

Vascular Endothelial Growth Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 23203097
DOI: 10.3390/ijms131114845
PMCID: PMC3509613

Genes

VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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