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Article

Influence of VEGF-A gene variation and protein levels in breast cancer susceptibility and severity.

International journal of cancer - 1 Sept 2007

Balasubramanian Sabapathy P, Cox Angelo, Cross Simon S, Higham Sue E, Brown Nicola J, Reed Malcolm W

Abstract excerpt

Vascular endothelial growth factor-A (VEGF-A) plays an important role in tumour angiogenesis and cancer progression. VEGF gene variation may influence VEGF levels and therefore cancer susceptibility and progression. We studied the role of VEGF single nucleotide polymorphisms and haplotypes in breast cancer susceptibility and severity. We also studied the relationships of VEGF SNPs with circulating VEGF levels in...

Topics

Aged
Base Sequence
Breast Neoplasms
Case-Control Studies
Cohort Studies
DNA Primers
Female
Haplotypes
Humans
Middle Aged
Neoplasm Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Tissue Array Analysis

Vascular Endothelial Growth Factor A

Source

Identifiers

PMID: 17471570
DOI: 10.1002/ijc.22772

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-17471570-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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