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Article

Vascular endothelial growth factor polymorphisms affect gene expression and tumor aggressiveness in patients with breast cancer.

Molecular medicine reports - 1 Mar 2014

Sa-Nguanraksa Doonyapat, Kooptiwut Suwattanee, Chuangsuwanich Tuenjai, Pongpruttipan Tawatchai, Malasit Prida, O-Charoenrat Pornchai

Abstract excerpt

Vascular endothelial growth factor (VEGF) is one of the key modulators of angiogenesis. The highly polymorphic promoter and 5' untranslated region of VEGF have been associated with susceptibility to and aggressiveness of several types of cancer. To examine the functional role of VEGF polymorphisms at -634 and -1498 positions, VEGF mRNA and protein in breast cancer tissues were analyzed by quantitative polymerase...

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PMID: 24401996
DOI: 10.3892/mmr.2014.1890

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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